Rab1a and alpha-synuclein act specifically at an early on stage of autophagosome development: an abundance of alpha-synuclein or lack of Rab1a disrupted an early on acting section of the autophagy machinery known as Atg9 and blocked the forming of autophagosome precursors known as omegasomes. Alpha-synuclein’s blockade of autophagy could enhance the gradual accumulation of toxic proteins and dysfunctional mitochondria, sensitizing neurons to cell death.. Alpha-synuclein protein in Parkinson’s disease inhibits autophagy: Research A protein linked to Parkinson’s disease may cause neurodegeneration by inhibiting autophagy-the process where cells digest some of their contents-according to a study in the September 20 problem of the Journal of Cell Biology ( Autophagy serves to clear a number of toxic waste materials from cells, including misfolded proteins and defective mitochondria.That is the smoking gun which includes now been uncovered, thanks almost completely to the independent press and our relentless commitment to true investigative journalism. There is absolutely no such thing as ‘complete safety’ in virtually any medical procedure; not in something mainly because incredibly safe as massage therapy even. But the sad reality that the CDC, the vaccine sector and the vaccine zealots have got pushed the absurd delusion that vaccines are ‘absolutely secure’ – – i.e. They present ZERO risk – – can be an entrance of scientific quackery . For this reason the vaccine sector has lost the general public relations battle on vaccines: because everyone knows the CDC is certainly lying continuously.